About 23andMe
23andMe combines ancestry with selected genetic-health reports from a home saliva sample. Premium adds ongoing report access; Total Health goes further with clinical exome reports, partner-lab blood testing and clinician support.
Register your saliva kitReturn your sampleExplore your genetic reports
Offerings
Premium Ancestry + Health
$208.99
Then $99/yr
Genetic health, carrier and ancestry reports
Selected variants; premium reports require membership
Ancestry and selected genetic-health reports from an at-home saliva kit.
Total Health
$508.99
Then $199/yr
Genotyping + clinical exome reports
Two blood panels/year; smaller follow-up
Clinical exome reports, saliva genotyping, two blood panels a year and clinician support.
Reviews
What people praise
Discovering family connections
Customers enjoy finding relatives and exploring their ancestry, including making family connections or filling in parts of their background they did not previously know.
A simple testing process
Positive reviews describe a manageable kit process and results that are easy to browse, making it straightforward to start exploring their ancestry and traits.
More to explore over time
Reviewers enjoy returning to genetic updates and new ancestry details, finding that reports and family connections give them more to explore after their first results.
What people complain about
More features behind subscriptions
Some customers dislike repeated upgrade prompts or discovering that tools they expected to use, including previously available features, now require another payment.
Login and account support problems
Customers describe password or account-access problems that keep them from their results, with support exchanges that do not always lead to a prompt resolution.
Family-tree tools can be limiting
Some ancestry customers find family-tree tools confusing or limited, struggling to understand how DNA matches connect or wanting better ways to explore those relationships.
Stories about 23andMe
Laura Osman
Acting on an unexpected cancer-risk result
Laura had no known family history of breast or ovarian cancer when 23andMe flagged a BRCA1 variant. After clinical follow-up testing, she discussed her options with doctors and chose preventive surgery, taking action before a cancer diagnosis.
23andme.orgLillian Newman
A better conversation about statin side effects
Lillian had been struggling with severe muscle pain while taking a statin. Her 23andMe medication report gave her new information to discuss with her doctor, who lowered her dose; she reported managing her cholesterol without the same debilitating pain.
23andme.orgJarrod and Ginger Lyle
Following up before routine screening
A Christmas DNA kit flagged two MUTYH variants for Jarrod, prompting follow-up with his doctor. Colonoscopies found repeated growths of benign polyps, and further specialist advice helped him decide on surgery to reduce his future colorectal cancer risk.
23andme.orgThings to know
- Unused kits have a limited refund window.
For direct purchases, request a refund within 30 days of ordering and before submitting saliva; return instructions and deductions apply.
- Your selected plan renews annually.
Premium and Total Health renew annually; cancel auto-renewal before the next billing period.
- Research and matching are separate choices.
Research participation, relative sharing and sample storage are separate choices.
- Age and state rules depend on the tier.
Health services have age and state requirements; Total Health also requires eligible partner-lab visits.
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FAQs
How does Total Health differ from Premium?
Premium uses selected-variant genotyping for ancestry and genetic-health reports. Total Health adds clinical exome reports, blood testing and clinician support.


