Nucleus Genomics — Nucleus Health + Preview

What’s included

Included

Cancer Included

64 reports, including Risk score: Breast cancer; Risk score: Colorectal cancer; Risk score: Male breast cancer; Risk score: Ovarian cancer; Risk score: Prostate cancer; …

Heart and blood vessels Included

58 reports, including Risk score: Coronary artery disease; Risk score: Hypertension; Familial hypercholesterolemia 2; Hypercholesterolemia 1; Familial hypercholesterolemia 3; …; Inherited clotting disorders (such as Factor V Leiden and prothrombin) (Thrombophilia 3 due to protein C deficiency, autosomal dominant; Thrombophilia 3 due to protein C deficiency, autosomal recessive; Thrombophilia 5 due to protein S deficiency, autosomal recessive)

Brain health Included

Alzheimer's (APOE) (Risk score: Alzheimer's disease); Parkinson's disease (12 reports, including Risk score: Parkinson's disease; Parkinson's disease 22; Parkinson's disease 8; Parkinson's disease 1 and 4; VPS35-related Parkinson's disease; …)

Metabolic health Included

Celiac disease (Risk score: Celiac disease); Type 2 diabetes (7 reports, including Risk score: Type 2 diabetes; Type 2 diabetes, maturity-onset diabetes of the young (MODY) type 12, and pulmonary arterial hypertension; DNAJC3-related type 2 diabetes; GPD2-related type 2 diabetes; Type 2 diabetes and maturity-onset diabetes of the young (MODY) type 13; …); Hereditary hemochromatosis (Hemochromatosis, type 2B; Hemochromatosis, type 2A; Hemochromatosis, type 3; Hemochromatosis)

Carrier screening Included

Nucleus Preview

Medication response Included

Malignant hyperthermia susceptibility 1; Malignant hyperthermia susceptibility 5; Warfarin resistance

Named inherited reports: Includes BRCA1/BRCA2, Lynch, familial-heart and carrier reports; a negative result does not rule out every inherited condition or variant.
Alzheimer’s risk: Public report gene display names APOE; this does not verify an individual ε4 genotype report or treatment eligibility.
One person: Health and Preview are report areas in one kit. Partner/embryo testing requires a separate purchase.

Results

Report

**Nucleus health summary**
The desktop report groups genetic results and links to individual condition reports.
youtube.com
Member walkthrough

Results: Health and Preview genetic reports, plus advertised raw genome downloads.
Download: Advertised VCF, CRAM, SV, CNV and FASTQ downloads
Timing: About 4–6 weeks after laboratory receipt.

Help

Live consultation

Extra fee

A SteadyMD genetic counselor discusses your results with you for one hour for $99.

Getting tested

Collect both cheek swabs for the same person and return them in the supplied tube. New York customers must collect and mail the sample from outside New York.

Preparing for your test

Instructions: Follow supplied swab instructions; no specific fasting or medication-stop interval established.

About Nucleus Genomics

Nucleus sequences a home cheek-swab sample for inherited-condition, carrier, common-risk and trait reports. Health and Preview are report areas for one person, with genome-file downloads and renewing membership. A genetic-counselor appointment is an optional extra.

Complete registration and health questionsReturn cheek swabsExplore reports and genome files

Reviews

What people complain about

Reports can feel less detailed

Some sequencing customers find the ready-made analysis less informative than expected and turn to their raw files for further exploration, particularly when they want more detailed interpretation.

Things to know

Approved kit cancellations have a seven-day window.
A cancellation deduction applies; ordinary refunds end after the laboratory receives the sample.
Membership renews annually.
Personal genetic counseling is an optional extra.
External health-data research requires opt-in consent.
External PHI research is opt-in; internal validation, service sharing and legal disclosures have separate terms.
Collect outside New York.
New York customers may receive a kit there but must collect and mail the sample outside the state.

Alternatives

23andMe · Premium Ancestry + Health

Uses selected-variant genotyping and adds ancestry matching, rather than Nucleus whole-genome sequencing.

$208.99

tellmeGen · Advanced DNA Kit

Uses selected variants for health and ancestry instead of Nucleus whole-genome sequencing.

$159.99

Sequencing.com · Comprehensive Health

Another whole-genome option with raw files, a report marketplace and a different continuing-access plan.

$599

24Genetics · All in One

A selected-marker package delivered as PDFs rather than a whole-genome health account.

$299

FAQs

Are Health and Preview tests for two people?

No. They are report areas in a kit for one person. Both swabs belong to that person; a partner needs a separate purchase.

What does the first-year purchase include?

One US kit includes the test and required first-year membership, with free US shipping and prepaid return. Membership renews annually; tax is shown at checkout.

Are Health and Preview two people’s tests?

No. One kit includes both report areas for one person. Its two swabs are not two sequencing purchases; a partner needs another kit.

Is genetic counseling included?

No. Optional SteadyMD genetic counseling is $99 for one hour; Embryo and IVF+ have separate support terms.

Can I collect in New York?

A kit may be received in New York, but the sample must be collected and mailed from outside New York. This is a collection/return restriction, not a ban on New York residents.

Can I download my genome?

VCF, CRAM, SV, CNV and FASTQ downloads are advertised. Check access terms before your membership ends.

What if I wait to send the sample?

The laboratory must receive the sample within one year of ordering. Approved kit cancellations have a separate seven-day window.

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Nucleus Genomics Health + Preview