About SiPhox Health
SiPhox uses an upper-arm home blood sample for its longevity panels. Buy a panel once or choose a recurring membership with additional app support; the kit, measured results and membership benefits remain distinct.
Choose a one-time panel or membershipCollect and return your upper-arm sampleReview your dashboard results
Offerings
SiPhox Ultimate 360
$274
one-time
62 markers
A one-time mail-in panel using a self-collected upper-arm blood sample.
What’s included in SiPhox Ultimate 360
HDL Cholesterol (HDL-C)
The amount of cholesterol carried inside HDL particles in the blood.
Triglycerides
Fats circulating in the blood that store energy from food the body does not immediately use.
Apolipoprotein B (ApoB)
A protein carried by certain cholesterol-carrying particles; its amount reflects their total number.
Total Cholesterol
The combined amount of cholesterol carried by the major blood lipoprotein groups.
VLDL Cholesterol (VLDL-C)
Cholesterol attributed to VLDL particles, estimated or measured depending on the laboratory method.
Triglyceride to HDL RatioCalc
Calculated ratio of triglycerides to HDL cholesterol measured in the same blood sample.
Total Cholesterol to HDL RatioCalc
Calculated ratio of total cholesterol to HDL cholesterol, using measurements in the same units.
Apolipoprotein A1 (ApoA1)
A major protein in HDL particles, sometimes compared with ApoB in cholesterol-related assessments.
VLDL Cholesterol (VLDL-C)Calc
Cholesterol attributed to VLDL particles, estimated or measured depending on the laboratory method.
LDL-C/HDL-C RatioCalc
Calculated comparison of LDL cholesterol to HDL cholesterol, using amounts in the same units.
LDL-C to ApoB RatioCalc
A calculated comparison of LDL cholesterol and ApoB, not a direct measurement of LDL particle size.
ApoB/ApoA1 RatioCalc
Calculated comparison of ApoB and ApoA1 protein amounts, rather than a literal particle-count ratio.
LDL Cholesterol (LDL-C)Calc
The amount of cholesterol carried inside LDL particles, rather than the number of particles.
Lipoprotein(a) [Lp(a)]
The amount of Lp(a), a cholesterol-carrying particle whose concentration is largely inherited.
Hemoglobin A1c (HbA1c)
Percentage of hemoglobin with sugar attached, reflecting average blood sugar over roughly two to three months.
C-Peptide
A substance released alongside insulin that helps assess the body's own insulin production.
Estimated Average Glucose (eAG)Calc
An estimate of average blood sugar calculated from HbA1c, rather than measured directly.
Follicle-Stimulating Hormone (FSH)
A pituitary hormone that supports development of eggs in the ovaries and production of sperm.
Estradiol (E2)
The main estrogen during the reproductive years, produced primarily by the ovaries.
Total Testosterone
All testosterone circulating in blood, including protein-bound and unbound forms.
Dehydroepiandrosterone Sulfate (DHEA-S)
An adrenal hormone the body uses to make testosterone and estrogen.
Luteinizing Hormone (LH)
A pituitary hormone involved in ovulation and sex-hormone production in the ovaries and testes.
Sex Hormone-Binding Globulin (SHBG)
A protein made mainly by the liver that carries testosterone, estradiol and other sex hormones in blood.
Free TestosteroneCalc
The portion of testosterone circulating without being attached to blood proteins.
Concentration · Calculated
Cortisol
An adrenal hormone involved in stress response, metabolism, blood pressure and inflammation.
Testosterone to Cortisol RatioCalc
A calculated comparison of testosterone and cortisol concentrations, whose numerical scale depends on the units.
Cortisol to DHEA-S RatioCalc
Calculated comparison of cortisol and DHEA-S, two adrenal hormones whose levels change differently.
Prolactin
A pituitary hormone involved in milk production and reproductive regulation.
Free Androgen Index (FAI)Calc
An estimate of testosterone exposure, calculated from total testosterone and its binding protein, SHBG.
Free TestosteroneMen only
The portion of testosterone circulating without being attached to blood proteins.
Percentage
LH to FSH RatioCalcWomen only
A calculated comparison of two reproductive hormones, LH and FSH, from the same collection.
ProgesteroneWomen only
A hormone produced after ovulation and during pregnancy, measured at a particular point in time.
Thyroid-Stimulating Hormone (TSH)
A pituitary hormone that signals the thyroid gland to produce thyroid hormones.
Free T3 (Free Triiodothyronine)
The portion of thyroid hormone T3 circulating unbound to blood proteins.
Free T4 (Free Thyroxine)
The unbound portion of T4 thyroid hormone available to tissues, commonly considered alongside TSH.
Thyroid Peroxidase Antibodies (TPOAb)
Antibodies against an enzyme the thyroid uses to make thyroid hormones.
Thyroglobulin Antibodies (TgAb)
Antibodies that recognize thyroglobulin; they can also interfere with measurements of thyroglobulin itself.
TSH to Free T4 RatioCalc
A calculated comparison of TSH and free T4 from the same sample; its value depends on units.
Free T3/Free T4 RatioCalc
A calculated comparison of free T3 and free T4 thyroid hormones from the same blood sample.
Vitamin D (25-hydroxy)
The main circulating form of vitamin D, reflecting vitamin D from sunlight, food and supplements.
Ferritin
An iron-storage protein whose blood level generally reflects the body's iron stores.
Iron
Iron circulating in blood at collection, mostly attached to the transport protein transferrin.
Unsaturated Iron-Binding Capacity (UIBC)
The unused iron-binding capacity of transferrin, the protein that carries iron in blood.
Transferrin Saturation (TSAT)Calc
Percentage of iron-binding sites occupied, usually calculated from blood iron and total iron-binding capacity.
Vitamin B12
A vitamin needed for red blood cell formation, nervous-system function and DNA production.
Folate (Vitamin B9)
Vitamin B9, needed for making DNA, cell division and red blood cell production.
Total Iron-Binding Capacity (TIBC)
Estimated capacity of the blood's transferrin protein to bind and carry iron.
C-Reactive Protein (CRP)
A liver-made protein that rises in response to inflammation, measured with conventional or high-sensitivity assays.
High-sensitivity C-reactive protein (hs-CRP)
Alanine Aminotransferase (ALT)
A liver-cell enzyme that can enter the blood when those cells are damaged.
Aspartate Aminotransferase (AST)
An enzyme in the liver, muscles and other tissues that can enter blood when cells are damaged.
Alkaline Phosphatase (ALP)
An enzyme found especially in the liver, bile ducts and bones.
Direct Bilirubin
The bilirubin fraction that reacts directly in the laboratory test; its contents depend on the method.
Total Bilirubin
The combined direct and indirect forms of bilirubin, a waste product from red-cell breakdown.
AST to ALT RatioCalc
A calculated comparison of AST and ALT enzyme activity from the same blood sample.
Gamma-Glutamyl Transferase (GGT)
An enzyme assessed alongside other findings when investigating liver or bile-duct injury.
Creatinine
A waste product from normal muscle activity that the kidneys mainly remove from blood.
Blood Urea Nitrogen (BUN)
Nitrogen from urea in blood, a waste product formed when the body breaks down protein.
Estimated Glomerular Filtration Rate (eGFR)Calc
An estimate of kidney filtration calculated from blood markers such as creatinine or cystatin C.
BUN/Creatinine RatioCalc
A calculated comparison of blood urea nitrogen with creatinine from the same collection.
Hemoglobin (Hgb)
The iron-containing protein in red blood cells that carries oxygen around the body.
Hematocrit (Hct)Calc
The share of your blood volume occupied by red blood cells.
Calculated
Albumin
A liver-made blood protein that helps retain fluid and transport other substances.
Total Protein
The combined concentration of albumin and globulins, the main groups of blood proteins.
Add-ons
A separately priced upgrade to a recurring SiPhox testing cycle.
A separately priced upgrade to a recurring SiPhox testing cycle.
Before you buy
- Preparation
- Follow the collection and preparation instructions supplied with your kit.
Results
- Results
- A digital biomarker dashboard with PDF results and personalized insights.
- Access
- Web
- Download
- PDF results
- Timing
- Typically 7–10 days.
Collection
Use the supplied upper-arm device at home and mail the sample to the laboratory. Follow the panel’s fasting and return instructions.
Reviews
Trustpilot
App Store
Google Play
BBBWhat people praise
Guidance through sample collection
Customers praise patient staff who walk them through collection and answer questions, helping them feel more confident about completing a home test correctly.
What people complain about
Collection can be harder than expected
Some customers find the kit difficult to use or cannot collect enough blood despite following the instructions, leading to frustration before any results are available.
Results take longer than expected
Customers describe waiting beyond the expected turnaround and receiving limited updates, particularly frustrating when they planned to use the results for an upcoming appointment or treatment discussion.
Extras complicate the purchase
Some customers find membership charges or repeated add-on offers confusing, saying the checkout experience makes it harder to understand the full cost of the test they wanted.
Stories
Colin Godby
An iron result that led to follow-up care
Despite being physically active, Colin’s first SiPhox test showed unusually high ferritin. That result started a medical follow-up that identified hemochromatosis, allowing him to begin treatment for an issue he had not realized was there.
siphoxhealth.comM. T.
Looking beyond apparently reassuring cholesterol
M. T. was running half-marathons and had been reassured about mildly raised cholesterol. SiPhox results prompted further heart checks, which revealed coronary artery disease; after receiving two stents, the member reported returning to running with improved markers.
siphoxhealth.comWilliam
Turning home bloodwork into an action plan
William used SiPhox to look more closely at his metabolic, cardiovascular and hormone markers. After receiving the results, a one-to-one consultation answered his questions and produced a follow-up plan based on his own data and concerns.
siphoxhealth.comThings to know
- Cancel billing separately from account deletion.
Shipped subscription periods are nonrefundable and test kits cannot be returned. Incomplete-sample credits or replacements are evaluated case by case.
- A one-time test and membership are different choices.
Membership adds recurring panels and digital support; additional testing is charged separately.
- Research and AI processing are permitted.
SiPhox’s policy allows service sharing, research and AI processing, and use of aggregated data.
- Use the upper-arm collection kit.
Follow fasting, collection and prompt sample-return instructions supplied with the panel.
Alternatives
Superpower · Membership
An annual venous blood draw with care-team messaging rather than upper-arm self-collection.
$199/year
Mito Health · Core Panel
A broad one-time blood-and-urine panel at a laboratory, with optional membership pricing.
$291.75
Everlywell · Everlywell 360
An annual Quest panel and written Care Plan rather than home upper-arm collection.
$399/year
Parsley Health · Advanced Lab Panel + Review
Adds a scheduled virtual clinician review and follow-up messaging to a venous blood panel, rather than home digital testing alone.
$550FAQs
Do I have to subscribe?
Longevity Essentials can be bought once. Membership adds recurring testing and app benefits; standalone upgrades have their own purchase terms.