About 23andMe
23andMe combines ancestry with selected genetic-health reports from a home saliva sample. Premium adds ongoing report access; Total Health goes further with clinical exome reports, partner-lab blood testing and clinician support.
Register your saliva kitReturn your sampleExplore your genetic reports
Offerings
23andMe Premium Ancestry + Health
$208.99
initial purchase
Then $99/year
Genetic health, carrier and ancestry reports
Selected variants; premium reports require membership
Ancestry and selected genetic-health reports from an at-home saliva kit.
What’s included in 23andMe Premium Ancestry + Health
Included
8 reports, including Risk score: Breast Cancer (available for females only); Risk score: Colorectal Cancer; Hereditary Prostate Cancer (HOXB13-Related); Risk score: Prostate Cancer (available for males only); Risk score: Skin Cancer (Basal and Squamous Cell Carcinomas); …
8 reports, including Risk score: Atrial Fibrillation; Risk score: Coronary Artery Disease; Risk score: HDL Cholesterol; Risk score: High Blood Pressure; Risk score: LDL Cholesterol; …; Inherited clotting disorders (such as Factor V Leiden and prothrombin) (Hereditary Thrombophilia)
Alzheimer's (APOE) (Late-Onset Alzheimer's Disease); Parkinson's disease (Parkinson's Disease)
Type 2 diabetes (Risk score: Type 2 Diabetes); Celiac disease (Celiac Disease); Hereditary hemochromatosis (Hereditary Hemochromatosis (HFE-Related))
46 reports, including ARSACS; Agenesis of the Corpus Callosum with Peripheral Neuropathy; Autosomal Recessive Polycystic Kidney Disease; Beta Thalassemia and Related Hemoglobinopathies; Bloom Syndrome; …
CYP2C19 Drug Metabolism; DPYD Drug Metabolism; SLCO1B1 Drug Transport
Not included
- Scope
- Selected reports do not constitute a broad diagnostic rare-disease workup. No purchased oral-microbiome report was listed.
Before you buy
- Saliva preparation
- No food, drink, smoking, gum, tooth brushing or mouthwash for 30 minutes before collection.
Results
Report
A genetic result with an explanation and guidance on using the report.
Official sample- Results
- Genetic reports in your account, with ancestry tools and the health reports in your selected plan.
- Access
- WebiPhoneAndroid
- Download
- Genotype text file in a ZIP, usually available within a week of requesting it.
- Timing
- About 3–4 weeks after the lab receives the saliva sample.
Help
AI assistant
IncludedDaNA answers general educational questions without access to your results.
Collection
Register the saliva kit in your 23andMe account, collect at home and use the supplied return mailer. Total Health also includes separate Quest blood visits.
Reviews
Trustpilot
App Store
Google PlayWhat people praise
Discovering family connections
Customers enjoy finding relatives and exploring their ancestry, including making family connections or filling in parts of their background they did not previously know.
A simple testing process
Positive reviews describe a manageable kit process and results that are easy to browse, making it straightforward to start exploring their ancestry and traits.
More to explore over time
Reviewers enjoy returning to genetic updates and new ancestry details, finding that reports and family connections give them more to explore after their first results.
What people complain about
More features behind subscriptions
Some customers dislike repeated upgrade prompts or discovering that tools they expected to use, including previously available features, now require another payment.
Login and account support problems
Customers describe password or account-access problems that keep them from their results, with support exchanges that do not always lead to a prompt resolution.
Family-tree tools can be limiting
Some ancestry customers find family-tree tools confusing or limited, struggling to understand how DNA matches connect or wanting better ways to explore those relationships.
Stories
Laura Osman
Acting on an unexpected cancer-risk result
Laura had no known family history of breast or ovarian cancer when 23andMe flagged a BRCA1 variant. After clinical follow-up testing, she discussed her options with doctors and chose preventive surgery, taking action before a cancer diagnosis.
23andme.orgLillian Newman
A better conversation about statin side effects
Lillian had been struggling with severe muscle pain while taking a statin. Her 23andMe medication report gave her new information to discuss with her doctor, who lowered her dose; she reported managing her cholesterol without the same debilitating pain.
23andme.orgJarrod and Ginger Lyle
Following up before routine screening
A Christmas DNA kit flagged two MUTYH variants for Jarrod, prompting follow-up with his doctor. Colonoscopies found repeated growths of benign polyps, and further specialist advice helped him decide on surgery to reduce his future colorectal cancer risk.
23andme.orgThings to know
- Cancel renewal before the next billing period.
Access continues until the paid period ends. Basic reports remain after premium access ends.
- The selected plan renews annually.
The first year is included in the purchase; renewal and clinical-service terms follow the selected plan.
- Research and matching are separate choices.
Research participation, relative sharing and sample storage are optional choices. Deletion has legal record-retention exceptions.
- Age and state rules depend on the tier.
The genetic-health service is for eligible adults; follow the selected plan’s state requirements.
Alternatives
Nucleus Genomics · Health + Preview
Uses whole-genome sequencing with optional counseling, compared with 23andMe’s selected-variant reports and clinical exome tier.
$538
tellmeGen · Advanced DNA Kit
A selected-variant health-and-ancestry kit without Total Health’s blood-testing and clinician membership.
$159.99
Sequencing.com · Comprehensive Health
Centers on whole-genome files and a report platform, rather than 23andMe’s ancestry service and optional Total Health clinical membership.
$599
24Genetics · All in One
Delivers emailed PDF reports instead of 23andMe’s interactive reports; the US package excludes pharmacogenetics.
$299FAQs
Does this sequence my whole genome?
No. Premium uses selected-variant genotyping.
Can I download my DNA data?
A raw genotype text file is available in a ZIP. This is not a whole-genome file.
Can I get a refund?
For unused direct-purchase kits, request within 30 days of order before sending saliva, and return the kit within 30 days of the request. Deductions may apply; partial membership periods are not refunded.